（令和2年4月よりテニュア付与のため、令和2年3月31日までの研究論文状況）

【研究論文】
Takuhiro Otosu, Kunihiko Ishii, and Tahei Tahara
“Multifocus Fluorescence Correlation Spectroscopy with Spatially Separated Excitation Beams”
Bull. Chem. Soc. Japan 92, 1495-1502 (2019).

Takuhiro Otosu and Shoichi Yamaguchi
“Reduction of glass-surface charge density slows the lipid diffusion in the proximal leaflet of a supported lipid bilayer”
J. Chem. Phys. 151, 025102 (2019).

Takuhiro Otosu and Shoichi Yamaguchi
“Total Internal Reflection Two-dimensional Fluorescence Lifetime Correlation Spectroscopy”
J. Phys. Chem. B 122, 5758-5764 (2018).

Takuhiro Otosu and Shoichi Yamaguchi
“Quantifying the Diffusion of Lipids in the Proximal/Distal Leaflets of a Supported Lipid Bilayer by Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy” J. Phys. Chem. B 122, 10315-10319 (2018).

Takuhiro Otosu and Shoichi Yamaguchi
“Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy: Concepts and Applications”
Molecules 23, 2972 (2018).
DOI:10.3390/molecules23112972

Takuhiro Otosu, Kaito Kobayashi and Shoichi Yamaguchi
“Local pH at the surface of hen egg white lysozyme”
Chemical Physics Letter 693, 165-169 (2018) DOI: 10.1016/j.cplett.2018.01.026

Takuhiro Otosu, Shoichi Yamaguchi
“Communication: Development of Standing Evanescent-Wave Fluorescence Correlation Spectroscopy and its Application to the Lateral Diffusion of Lipids in a Supported Lipid Bilayer”
The Journal of Chemical Physics 147, 041101 (2017)
DOI: 10. 1063/1.4985871

Takuhiro Otosu, Kunihiko Ishii, Hiroyuki Oikawa, Munehito Arai, Satoshi Takahashi, and Tahei Tahara
“Highly Heterogeneous Nature of the Native and Unfolded States of the B Domain of Protein A Revealed by Two-Dimensional Fluorescence Lifetime Correlation Spectroscopy”
The Journal of Physical Chemistry B 2017, 121, 5463-5473
DOI: 10.1021/acs.jpcb.7b00546

Otosu, T., Ishii, K. & Tahara, T.
“Microsecond protein dynamics observed at the single molecule level”
Nature Communications 6, 7685, 2015

Otosu, T., Ishii, K. & Tahara, T.
“Simple Calibration of the Counting-rate Dependence of the Timing Shift of Single Photon Avalanche Diodes by Photon Interval Analysis”
Rev. Sci. Instrum., 84, 036105, 2013

Otosu, T., Nishimoto, E. & Yamashita, S.
“Multiple Conformational State of Human Serum Albumin around Single Tryptophan Residue at Various pH Revealed by Time-resolved Fluorescence Spectroscopy”
Journal of Biochemistry, 147(2), 191-200, 2010

Otosu, T., Nishimoto, E. & Yamashita, S.
“Fluorescence Decay Characteristics of Indole Compounds Revealed by Time-resolved Area-normalized Emission Spectroscopy”
Journal of Physical Chemistry A, 113, 2847-2853, 2009

Fukunaga, Y., Nishimoto, E., Otosu, T., Murakami, Y. & Yamashita, S.
“The Unfolding of α-Momorcharin Proceeds Through the Compact Folded Intermediate”
Journal of Biochemistry, 144, 457-466, 2008

Otosu, T.,. Nishimoto, E. & Yamashita, S.
“Spectrally and Time-resolved Fluorescence Spectroscopic Study on Melittin–Calmodulin Interaction”
Journal of Biochemistry, 142, 655-661, 2007

Fukunaga, Y., Nishimoto, E., Yamashita, K., Otosu, T. & Yamashita, S.
“The Partially Unfolded State of β-Momorcharin Characterized with Steady-state and Time-resolved Fluorescence Studies”
Journal of Biochemistry, 141, 9-18, 2007

[国内学会発表(一般講演)]

定在エバネッセント波を用いた蛍光相関分光装置の開発と脂質二重膜への応用
日本化学会第96回春季年会，2016年3月
乙須拓洋，山口祥一

[シンポジウム等の企画・開催]

2016年1月13日：埼玉大学研究機構テニュアトラック第5回シンポジウム「脳システムの作動原理とその形成」